Stroke | Types , Management and Rehabilitation
Table of Contents
Introduction Of Stroke
A stroke (cerebrovascular accident [CVA]) is the sudden misfortune of neurological function caused by an interruption of blood flow to the brain. Ischemic stroke is the most common type, affecting about 80%of individuals with stroke, and can be the result of thrombosis, embolism, or hypoperfusion. Hemorrhagic stroke occurs when blood vessels burst, causing leakage of blood in or around the brain.

Types of Strokes
It are the classified by etiologic categories (embolus, thrombosis, or hemorrhage), specific
vascular territory (anterior cerebral artery syndrome middle cerebral artery syndrome.), and management
categories (minor stroke, major stroke, deteriorating stroke, young stroke, transient ischemic attack ).
Here we will explain both the vascular and management category
Etiologic Categories
Thrombosis
The stroke occurring because the thrombus (blood clot)block the major blood vessels of brain which stop the oxygen supply in various parts of brain. The formation of thrombus occur inside blood vessels or the chamber of heart .
Embolus
The stroke occurring because the emboli (blood clot or other foreign material such as, tumor cells) block the major blood vessels of brain which stop the oxygen supply in various parts of brain. The formation of emboli occur inside blood vessels or the chamber of heart .
Hemorrhage
The stroke occurs because of the rupture of the major blood vessels which lead to blood accumulation in various parts of the brain.
Vascular Category
The vascular category means the stroke occurs due to damage in major and minor blood vessels of the brain or a circle of wills. It consists of Anterior Cerebral Artery Syndrome, Middle Cerebral Artery Syndrome, Internal Carotid Artery Syndrome, Posterior Cerebral Artery Syndrome, Lacunar Stroke, and vertebrasilar artery Syndrome. Let us understand them individually.
Anterior Cerebral Artery Syndrome (ACA)
The anterior cerebral artery (ACA) is the first and smaller of two terminal branches of the internal carotid artery is blocked (infarct) causing no blood supply in the anterior regions of the brain resulting in anterior Cerebral Artery Syndrome.
It supplies the medial aspect of cerebral hemisphere (frontal and parietal lobes) and subcortical structures, including basal ganglia ( inferior caudate nucleus, anterior internal capsule.), anterior fornix, and anterior four-fifths of the corpus callosum.
Sign and symptoms
The most common characteristics of ACA disorder include contralateral hemiparesis and sensory loss with greater involvement of the lower extremity (LE) than the upper extremity (UE). Other symptoms are
- Urinary incontinence
- Apraxia
- Abulia (akinetic mutism)
- Contralateral grasp reflex, sucking reflex
Middle Cerebral Artery Syndrome
The middle cerebral artery (MCA) is the second of the internal carotid artery’s two main branches blocked (infarct), causing no blood supply in the brain’s middle regions, resulting in MCA syndrome.
It supplies the entire lateral aspect of the cerebral hemisphere (frontal, temporal, and parietal lobes) and subcortical structures, including the internal capsule (posterior portion), corona radiata, Globus pallidus (outer part), most of caudate nucleus, and the
putamen.
Sign and symptoms
The most common characteristics of MCA syndrome are contralateral spastic hemiparesis(weakness ) and sensory loss of the face, UE, and LE, with the face and UE more involved than the LE. Other symptoms are as follows
- Motor speech impairment: Broca or nonfluent aphasia with limited vocabulary and slow, hesitant speech
- Receptive speech impairment: Wernicke or fluent aphasia with impaired auditory comprehension and fluent speech with normal rate and melody
- Global aphasia: nonfluent speech with poor comprehension
- Perceptual deficits: unilateral neglect, depth perception, spatial relations, agnosia
- Limb-kinetic apraxia
- Loss of conjugate gaze to the opposite side
- Ataxia of contralateral limb(sensory ataxia)
Posterior Cerebral Artery Syndrome
The two posterior cerebral arteries (PCAs) arise as terminal branches of the basilar artery are blocked (infarct), causing no blood supply in the brain’s posterior regions, resulting in PCA syndrome.
They supply the corresponding occipital lobe and medial and inferior temporal lobe. They also supply the upper brain stem, midbrain, and posterior diencephalon, including most of the thalamus.
Sign and symptoms
- The patient will have a contralateral sensory loss(the medical term is Hemianesthesia ).
- The might feel central post-stroke (thalamic )pain.
- The person will have difficulty in reading and writing.
- medical terms are dyslexia and agraphia )
- Sometimes he/she might have a problem naming people on sight.
- Temporal lobe ischemic can result in memory loss (the medical term is amnesia )
Lacunar Stroke
Lacunar strokes are caused by small vessel disease deep in the cerebral white matter (penetrating artery disease). When one or more small arteries are involved in hemorrhage or become blocked, resulting in ischemia of a small area is called lacunar syndromes /lacunar stroke .
Sign and symptoms
- These types of Patients feel central post-stroke (thalamic) pain.
- Weakness or numbness usually on one side of face, arm, or leg etc.
- The person will have difficulty in reading and writing.
- Difficulty in walking
- Vision changes (blurred vision, double vision)
- Difficulty with swallowing
- Dizziness or vertigo
Vertebrobasilar Artery Syndrome
The occlusion in vertebral arteries which arise from the subclavian arteries and travel into the brain along the medulla where they merge at the inferior border of the pons to form the basilar artery causes Vertebrobasilar Artery Syndrome
These arteries supply the cerebellum (via posterior inferior cerebellar arteries) and the medulla (via the medullary arteries). The basilar artery supplies pons (via pontine arteries), the internal ear (via labyrinthine arteries), and the cerebellum (via the anterior inferior and superior cerebellar arteries). The basilar artery then terminates at the upper border of the pons, giving rise to the two posterior arteries
- The Patients develop acute hemiparesis rapidly progressing to tetra plegia and lower bulbar paralysis (CNs V through XII are involved).
- Initially, the patient is dysarthric and dysphonic but rapidly progresses to mutism (anarthria).
- The patient cannot move or speak but remains alert and oriented. There is no loss of consciousness and sensation
- t cannot move or speak but remains alert and oriented. Horizontal eye movements are impaired, but vertical eye movements and blinking remain intact.
Extracranial injuries such as ,Forceful neck motions (e.g., whiplash or aggressive neck manipulations) to the vertebral arteries as they travel through the cervical spine can also produce verte brobasilar signs and symptoms.
- Dizziness and vertigo
- Nausea and vomiting
- Double vision
- Slurred speech
- Weakness, numbness, or tingling in face , arm or leg
- Difficulty in swallowing or dysphagia
- Nystagmus
Management Categories
Management categories for strokes are based on its severity and location of the stroke, as well as overall health of individual. The main categories are ;
Transient ischemic attack (TIA)
ancient ischemic attack (TIA) refers to the temporary interruption of blood supply to the brain .It last for only a few min utes or for several hours but by definition do not last longer than 24 hr.It is a warring sign of body that their an residual brain damage or permanent neurological dysfunction.
Deteriorating stroke
The term deteriorating stroke refers to the patient whose neurological status deteriorates after admission to the hospital. This change in status may be due to cerebral or systemic causes (e.g., cerebral edema, progressing thrombosis).
Young stroke
The Stroke affecting any persons younger than age 45 years is called Young stroke .The major causes of stroke in children include perinatal arterial ischemic stroke, sickle cell dis ease, congenital HD, thrombophlebitis, and trauma.
Stroke mimics
The condition that mimic like stroke symptoms but it is not actually stroke is called Stroke mimics. (e.g., Seizures, Migraine
What are Treatment Options for Stroke Patients?
Medical Management Of Stroke
Medical management of stroke involves all the emergency management of the patient’s recovery from a critical condition.
- Improve cerebral perfusion by reestablishing circulation and oxygenation and assist in stopping the progression of the lesion to limit deficits. Oxygen is delivered via a mask or nasal cannula. Patients in a coma may require intubation or assisted ventilation and suctioning.
- Maintain adequate BP. Hypotension or extreme hypertension is treated; antihypertension agents have the added risk of inducing hypotension and decreasing cerebral perfusion.
- Restore/maintain fluid and electrolyte balance.
- Control seizures and infections.
- Control edema, intracranial pressure, and herniation using antiedema agents. Ventriculostomy may be indicated to monitor and drain cerebrospinal fluid.
- Maintain bowel and bladder function, which may include a urinary catheter. Catheterization is typically short-term but may be long-term with the patient in a coma.
Pharmacological Management
- Thrombolytics: These are used to dissolve the clots in coronary arteries, pulmonary emboli, and deep vein thrombosis [DVT].For example, alteplase and tenecteplase
- Anticoagulants: Used to reduce the risk of blood clot formation
and prevent existing clots from getting bigger by thinning the blood. Examples are warfarin [Coumadin], heparin, and dabigatran etexilate [Pradaxa]. - Antiplatelet therapy: It prevents platelets (blood cells) from sticking together. Examples , acetylsalicylic acid [aspirin]; clopidogrel bisulfate [Plavix]; dabigatran etexilate [Pradaxa].
- Antihypertensive agents: ACE inhibitors, alpha-blockers [Minipress], beta-blockers, calcium channel blockers, direct vasodilators, diuretics, and postganglionic neuron inhibitors.
- Angiotensin II receptor antagonists: By blocking angiotensin II, a chemical that triggers muscle contraction around blood vessels, narrowing them; enlarges blood vessels, and reduces blood pressure. Examples; are telmisartan [Micardis], and losartan potassium [Cozaar, Hyzaa].
- Anticholesterol agents: They help to lower cholesterol by inhibiting the enzyme in the blood that produces cholesterol in the liver.Example; atorvastatin calcium [Lipitor], rosuvastatin calcium [Crestor], simvastatin [Zocor],
- Antispasmodics: Used to relax skeletal muscle and decrease muscle spasms. Examples: carisoprodol [Soma], chlorzoxazone [Parafon Forte], cyclobenzaprine [Flexeril]. Antispastics also work the same Some examples are baclofen [Lioresal], dantrolene sodium [Dantrium], and diazepam [Valium].
- Anticonvulsants: Used to control seizures; act as a generalized central nervous system depressant. Example,carbamazepine [Tegretol], clonazepam [Klonopin], diazepam [Valium].
- Antidepressants: Used to control depression. Examples are fluoxetine [Prozac], monoamine oxidase inhibitors, and sertraline [Zoloft].
Neurosurgical Management Of Stroke.
Neurosurgical interventions for stroke patients may include the following:
Mechanical thrombectomy: It is a surgical procedure where there is the removal of a large blood clot by sending a stent retriever to the site of the blocked blood vessel in the brain. To remove the
brain clot, a catheter is threaded through an artery in the groin up to the blocked artery in the brain where the clot is removed. The procedure should be done
within 6 hr of acute stroke symptoms.
Carotid endarterectomy: It is a surgical procedure used to remove fatty deposits from the carotid artery. It is a useful procedure to prevent recurrent strokes or the development of stroke in individuals with TIAs.
In typical guidelines, stenosis is used whenever surgery is considered for stroke of 60% to 99%. It can reduce stroke risk by as much as 55%. It cannot be performed with acute stroke.
Rehabilitation Of Stroke
Rehabilitation is a set of interventions that is a combination of a physician, nurse, physical therapist, occupational therapist, speech-language pathologist, and social worker many more. This treatment method is designed to help individuals regain independence in daily activities, participate in work, education, and recreation, and achieve meaningful life roles.
The team of rehabilitation specialists includes a physician, nurse, physical therapist, occupational therapist, speech-language pathologist, and social worker. Additional others may include a neuropsychologist, nutritionist, recreational therapist, or vocational counselor. The patient/client, family, and caregivers, all should be involved in all decision-making regarding the POC.
The National Stroke Association instituted a process to certify stroke rehabilitation specialists. The designation of clinical stroke rehabilitation specialist (CSRS) ensures that therapists are expert stroke clinicians through a rigorous set of courses and written examinations and a nationally recognized credential, the CSRS certification